Non-stop flights from Florence (FLO)
Florence Airport (IATA: FLO, ICAO: KFLO), also known as Florence Regional Airport, is a small airport in United States with domestic flights only.Florence Airport has non-stop passenger flights scheduled to only one destination.
At present, there is one domestic flight from Florence.
The only flight from Florence FLO is a 99 mile (159 km) non-stop route to Charlotte CLT, which takes around 1 hour and 7 minutes.
On this page
Airlines flying from Florence Popular destinations from Florence Popular destinations with a stopover Points & Miles information Destinations by flight duration Best time to travel from Florence International flights Domestic flights Alternative airports FAQAirlines flying from Florence
Only one airline is flying from and to Florence, which is American Airlines.
Popular destinations from Florence
Below you can find a list of the most popular destinations from Florence, based on the number of scheduled flights for this month.
Popular destinations with a stopover
Aside from all non-stop destinations listed above, these are popular destinations from Florence that require a stopover:
Information on Points & Miles
This section lists destinations within specific distances from Florence. It's helpful if you're seeking destinations covering certain mileage, which can be useful when planning an award flight or booking with points and miles.
For more flexibility in choosing distances, consider upgrading to FlightConnections Premium. You'll gain access to the distance filter and many other useful features to refine your search!
From Florence, which places within 500 miles can I reach?

Destinations from Florence by flight duration
Discover a variety of destinations from Florence below, organized by flight duration. This layout allows you to easily identify destinations based on the maximum flight duration you prefer. Additionally, you can utilize the duration filter on the map, which is even more convenient!
Where can I fly from Florence within 2 hours?

Best time to travel from Florence
From Florence, you can fly directly to places, each offering a experience. Below, you'll find helpful information to plan your trip at the ideal time of the year!
🌺 💦 Humid Subtropical destinations
There are direct flights available to one Humid Subtropical / Warm Temperate destination. Known for their hot, humid summers, with temperatures around 30°C (86°F), and mild winters, these destinations feature lush greenery and year-round rainfall. You'll discover a blend of beautiful beaches, dense forests, and lively cities, offering abundant outdoor adventures, cultural sights, and city attractions to explore.
🌐 In the Northern Hemisphere:
These destinations can be enjoyed year-round, but the best times to visit are from April to June or from August to October

International flights from Florence
Currently there are no international flights departing from Florence. To get from Florence to another country you will need a flight with a stopover through Charlotte.
Domestic flights from Florence
Flights from Florence to United States
There is just one domestic flight from Florence, which is between Florence and Charlotte. Direct flights to Charlotte are offered by American Airlines (Oneworld).
All flights to United States
Alternative airports near Florence
Below you can find a list of alternative airports to Florence (FLO). The nearest airports to Florence (FLO) are Myrtle Beach (MYR) and Fayetteville (FAY).
Frequently asked questions - FAQ
How many airports are there in Florence?
There is 1 airport in Florence: Florence Regional Airport (FLO).
What is the best airport to fly from Florence?
The most convenient airport to fly from Florence is Florence Regional Airport (FLO).
How many airlines fly from Florence?
There is 1 airline flying from Florence, which is American Airlines, as of April 2026.
Which airlines fly from Florence?
American Airlines is the only airline flying from Florence.
Which alliances are flying from Florence?
Oneworld is currently the only alliance flying from Florence.
How many nonstop flights are there from Florence?
There are roughly 60 flights departing from Florence every month (or 14 flights each week), to a total of 1 airports - all within United States.
What is the official name of Florence Airport?
The official name of Florence Airport is Florence Regional Airport.
What is the airport code of Florence Airport?
The airport code of Florence Airport is FLO.
What are the most popular flights from Florence?
Charlotte is the only direct flight destination from Florence.
How long is the flight from Florence?
| Florence to Charlotte | 1h 7m |